Identification of nitric oxide as an endogenous inhibitor of 26S proteasomes in vascular endothelial cells.
The 26S proteasome plays a fundamental role in almost all eukaryotic cells, including vascular endothelial cells. However, it remains largely unknown how proteasome functionality is regulated in the vasculature. Endothelial nitric oxide (NO) synthase (eNOS)-derived NO is known to be essential to mai...
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| Main Authors: | Hongtao Liu, Shujie Yu, Hua Zhang, Jian Xu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2014-01-01
|
| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0098486 |
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