Clinicopathological study and molecular subtyping of muscle-invasive bladder cancer (MIBC) using dual immunohistochemical (IHC) markers

Clinicopathological study and molecular subtyping of muscle-invasive bladder cancer (MIBC) using dual immunohistochemical (IHC) markers

Abstract Background Muscle-invasive bladder carcinomas (MIBCs) exhibit significant heterogeneity, with diverse histopathological features associated with varied prognosis and therapeutic response. Although genomic profiling studies have identified several molecular subtypes of MIBC, two basic molecu...

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Main Authors: R. Vaithegi, Kanthilatha Pai, Anuradha Calicut Kini Rao, Vidya Monappa, Swathi Prabhu, Nischitha Suvarna
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Diagnostic Pathology
Subjects:
Muscle-invasive bladder carcinoma
Molecular subtypes
Immunohistochemistry
GATA3
CK5/6
Luminal
Online Access:https://doi.org/10.1186/s13000-025-01603-8
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https://doi.org/10.1186/s13000-025-01603-8

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