Investigating the reassortment potential and pathogenicity of the S segment in Akabane virus using a reverse genetics system

Investigating the reassortment potential and pathogenicity of the S segment in Akabane virus using a reverse genetics system

Abstract Background Akabane virus (AKAV) is an arthropod-borne virus that causes congenital malformations and neuropathology in cattle and sheep. In South Korea, AKAVs are classified into two main genogroups: K0505 and AKAV-7 strains. The K0505 strain infects pregnant cattle, leading to fetal abnorm...

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Bibliographic Details
Main Authors: Eun-Jee Na, Chang-Gi Jeong, Su-Beom Chae, Jae-Ku Oem
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Veterinary Research
Subjects:
Akabane virus
Reverse genetics system
S segment
Reassortment
Suckling mouse
Pathogenicity
Online Access:https://doi.org/10.1186/s12917-024-04459-0
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https://doi.org/10.1186/s12917-024-04459-0

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