Serological Markers to Assess Liver Fibrosis and Their Roles
Chronic liver disease is a significant public health issue worldwide, with the degree of liver fibrosis and its progression significantly influencing the treatment and prognosis. A liver biopsy is the standard diagnostic method, but it is invasive and presents various issues. Therefore, numerous non...
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| Format: | Article |
| Language: | English |
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Jin Publishing & Printing Co.
2024-11-01
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| Series: | The Korean Journal of Gastroenterology |
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| Online Access: | https://www.kjg.or.kr/journal/view.html?uid=6058&vmd=Full |
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| author | Beom Kyung Kim |
| author_facet | Beom Kyung Kim |
| author_sort | Beom Kyung Kim |
| collection | DOAJ |
| description | Chronic liver disease is a significant public health issue worldwide, with the degree of liver fibrosis and its progression significantly influencing the treatment and prognosis. A liver biopsy is the standard diagnostic method, but it is invasive and presents various issues. Therefore, numerous non-invasive diagnostic methods have been developed. Serum markers are categorized into indirect
markers, which reflect liver damage, inflammation, or functional changes, and direct markers, which measure the components released into the bloodstream during fibrosis. In addition, various kinds of formulas that combined direct/indirect markers and demographic variables were developed and validated with encouraging outcomes. Nevertheless, despite their convenience, serum indicators require cautious interpretation because they are affected by a number of factors. More research will be needed to determine if the clinical course of chronic liver disease under a disease-specific treatment could be monitored appropriately using serological markers. |
| format | Article |
| id | doaj-art-2293147bd5b949ab887b838b778bfdf4 |
| institution | Kabale University |
| issn | 1598-9992 2233-6869 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Jin Publishing & Printing Co. |
| record_format | Article |
| series | The Korean Journal of Gastroenterology |
| spelling | doaj-art-2293147bd5b949ab887b838b778bfdf42025-01-03T05:05:25ZengJin Publishing & Printing Co.The Korean Journal of Gastroenterology1598-99922233-68692024-11-0184519520010.4166/kjg.2024.123Serological Markers to Assess Liver Fibrosis and Their RolesBeom Kyung Kim0https://orcid.org/0000-0002-5363-2496Department of Internal Medicine, Yonsei University College of Medicine; Institute of Gastroenterology, Yonsei University College of Medicine; Yonsei Liver Center, Severance Hospital, Yonsei University Health System, Seoul, KoreaChronic liver disease is a significant public health issue worldwide, with the degree of liver fibrosis and its progression significantly influencing the treatment and prognosis. A liver biopsy is the standard diagnostic method, but it is invasive and presents various issues. Therefore, numerous non-invasive diagnostic methods have been developed. Serum markers are categorized into indirect markers, which reflect liver damage, inflammation, or functional changes, and direct markers, which measure the components released into the bloodstream during fibrosis. In addition, various kinds of formulas that combined direct/indirect markers and demographic variables were developed and validated with encouraging outcomes. Nevertheless, despite their convenience, serum indicators require cautious interpretation because they are affected by a number of factors. More research will be needed to determine if the clinical course of chronic liver disease under a disease-specific treatment could be monitored appropriately using serological markers.https://www.kjg.or.kr/journal/view.html?uid=6058&vmd=Fullnon-invasivediagnosisliverfibrosisserology |
| spellingShingle | Beom Kyung Kim Serological Markers to Assess Liver Fibrosis and Their Roles The Korean Journal of Gastroenterology non-invasive diagnosis liver fibrosis serology |
| title | Serological Markers to Assess Liver Fibrosis and Their Roles |
| title_full | Serological Markers to Assess Liver Fibrosis and Their Roles |
| title_fullStr | Serological Markers to Assess Liver Fibrosis and Their Roles |
| title_full_unstemmed | Serological Markers to Assess Liver Fibrosis and Their Roles |
| title_short | Serological Markers to Assess Liver Fibrosis and Their Roles |
| title_sort | serological markers to assess liver fibrosis and their roles |
| topic | non-invasive diagnosis liver fibrosis serology |
| url | https://www.kjg.or.kr/journal/view.html?uid=6058&vmd=Full |
| work_keys_str_mv | AT beomkyungkim serologicalmarkerstoassessliverfibrosisandtheirroles |