Automated prediction of fibroblast phenotypes using mathematical descriptors of cellular features

Abstract Fibrosis is caused by pathological activation of resident fibroblasts to myofibroblasts that leads to aberrant tissue stiffening and diminished function of affected organs with limited pharmacological interventions. Despite the prevalence of myofibroblasts in fibrotic tissue, existing metho...

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Bibliographic Details
Main Authors: Alex Khang, Abigail Barmore, Georgios Tseropoulos, Kaustav Bera, Dilara Batan, Kristi S. Anseth
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-58082-0
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