Effects of 3D-printed exosome-functionalized brain acellular matrix hydrogel on neuroinflammation in rats following cerebral hemorrhage

Effects of 3D-printed exosome-functionalized brain acellular matrix hydrogel on neuroinflammation in rats following cerebral hemorrhage

Abstract Background Exosome-based therapeutics have garnered significant attention for intracerebral hemorrhage (ICH) treatment due to their capacity to regulate metabolic dysregulation, restore cellular homeostasis, and modulate the injury microenvironment via bioactive cargoes such as microRNAs an...

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Bibliographic Details
Main Authors: Aobo Zhang, Boyu Sun, Chengrui Nan, Lulu Cong, Zongmao Zhao, Liqiang Liu
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Stem Cell Research & Therapy
Subjects:
3D biological scaffold
dECM
hUCMSC-exos
dECM@exo
Intracerebral hemorrhage
Neuroinflammation
Online Access:https://doi.org/10.1186/s13287-025-04332-3
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https://doi.org/10.1186/s13287-025-04332-3

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