Proteogenomic approach to immunopeptidomics of ovarian tumors identifies shared peptide vaccine candidates

Proteogenomic approach to immunopeptidomics of ovarian tumors identifies shared peptide vaccine candidates

Abstract Epithelial ovarian cancers are largely comprised of immunogenic tumor sub-types with the degree of CD8+ T cell infiltration being prognostic of clinical outcome. Tumor antigen-specific T cells are identified among these infiltrating T cell populations which has spurred a decade of developme...

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Main Authors: Jacopo Chiaro, Karita Peltonen, Kadri Õunap, Aubrey Bailey, Sara Feola, Sara Wojciechowski, Masoumeh Es-Haghi, Mikel Azkargorta, Félix Elortza, Salvatore Russo, Hanna Sallinen, Maarit Anttila, Olga Gurvich, Vincenzo Cerullo, Tuija Kekarainen
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-025-01234-6
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https://doi.org/10.1038/s41541-025-01234-6

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