Genomic evidence for low genetic diversity but purging of strong deleterious variants in snow leopards

Genomic evidence for low genetic diversity but purging of strong deleterious variants in snow leopards

Abstract Background Long-term persistence of species with low genetic diversity is the focus of widespread attention in conservation biology. The snow leopard, Panthera uncia, is a big cat from high-alpine regions of Asia. However, its subspecies taxonomy, evolutionary history, evolutionary potentia...

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Main Authors: Lin Yang, Hong Jin, Qien Yang, Andrey Poyarkov, Miroslav Korablev, Viatcheslav Rozhnov, Junjie Shao, Qiaomei Fu, Jose Antonio Hernandez-Blanco, Xiangjiang Zhan, Li Yu, Dmitry Alexandrov, Qingyan Dai, Bariushaa Munkhtsog, Xin Du, Bayaraa Munkhtsog, Liqing Ma, Wanlin Chen, Sergei Malykh, Yipeng Jin, Shunfu He, Tongzuo Zhang, Guosheng Wu, Yonghong Shi, Fuwen Wei, Yibo Hu
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Genome Biology
Subjects:
Snow leopards
Population genomics
Genetic structure
Genomic diversity
Deleterious variants
EPAS1
Online Access:https://doi.org/10.1186/s13059-025-03555-0
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https://doi.org/10.1186/s13059-025-03555-0

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