Aneuploidy of specific chromosomes is beneficial to cells lacking spindle checkpoint protein Bub3.

Aneuploidy typically poses challenges for cell survival and growth. However, recent studies have identified exceptions where aneuploidy is beneficial for cells with mutations in certain regulatory genes. Our research reveals that cells lacking the spindle checkpoint gene BUB3 exhibit aneuploidy of s...

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Bibliographic Details
Main Authors: Pallavi Gadgil, Olivia Ballew, Timothy J Sullivan, Soni Lacefield
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-02-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1011576
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