Dioscin from smilax china rhizomes inhibits platelet activation and thrombus formation via up-regulating cyclic nucleotides
Abstract Cardiovascular disease, the leading cause of mortality in the United States, is caused by abnormal platelet accumulation and coagulation. Dioscin has been reported to suppress the growth of tumor-associated cells and trigger apoptosis. However, its mechanism in inhibiting platelet activatio...
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| Main Authors: | Ga Hee Lee, Jin Pyo Lee, Na Yoon Heo, Chang-Dae Lee, Gyeongchan Kim, Akram Abdul Wahab, Man Hee Rhee, Sanghyun Lee, Dong-Ha Lee |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-025-09452-7 |
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