Gut microbiome predictors of advanced therapy response in Crohn’s disease: protocol for the OPTIMIST prospective, longitudinal, observational pilot study in Canada

Gut microbiome predictors of advanced therapy response in Crohn’s disease: protocol for the OPTIMIST prospective, longitudinal, observational pilot study in Canada

Introduction Inflammatory bowel disease (IBD), including Crohn’s disease (CD) and ulcerative colitis, is characterised by chronic and relapsing inflammation of the gastrointestinal tract, leading to significant morbidity and reduced quality of life. The global rise in IBD incidence is driven by a co...

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Main Authors: Greg Rosenfeld, Susanna Meade, Yvette Leung, Astrid-Jane Williams, Gurpreet Kaur, Brian Bressler, Cristian Aldo Massaro, Fanny Laure Lemarié, Genelle Lunken
Format: Article
Language:English
Published: BMJ Publishing Group 2025-03-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/15/3/e094280.full
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https://bmjopen.bmj.com/content/15/3/e094280.full

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