Protocol for an observational study to assess the impact of pharmacogenetics on outcomes in vascular surgery (PROSPER)

Introduction Patients with chronic limb-threatening ischaemia (CLTI) are often prescribed clopidogrel in order to reduce their risk of major adverse limb and cardiovascular events. Clopidogrel is metabolised by the CYP2C19 enzyme and genetic variations in CYP2C19 are common. These variants can influ...

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Bibliographic Details
Main Authors: John H McDermott, William G Newman, Stuart Wright, Kerry Anne Burke, Selman Mirza, Nicholas S Greaves
Format: Article
Language:English
Published: BMJ Publishing Group 2025-05-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/15/5/e088456.full
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