Development and study of reactive hot-melt extruded granules based on interpolymer combinations of Eudragit® copolymers for indomethacin delivery

Introduction. As a result of the study, 4 types of pellets with indomethacin based on Eudragit® copolymers of EPO and L100-55 grades, their physical mixture (PM) being similar in composition to the synthesised interpolyelectrolyte complex (IPEC) EPO/L100-55 – 1.95 : 1 (mole/mole) were obtained using...

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Bibliographic Details
Main Authors: S. F. Nasibullin, T. Van Duong, I. Nikolakakis, K. Kachrimanis, G. Van den Mooter, R. I. Moustafine
Format: Article
Language:Russian
Published: LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2025-03-01
Series:Разработка и регистрация лекарственных средств
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Online Access:https://www.pharmjournal.ru/jour/article/view/2046
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