eIF4A inhibition allows translational regulation of mRNAs encoding proteins involved in Alzheimer's disease.

Alzheimer's disease (AD) is the main cause of dementia in our increasingly aging population. The debilitating cognitive and behavioral symptoms characteristic of AD make it an extremely distressing illness for patients and carers. Although drugs have been developed to treat AD symptoms and to s...

Full description

Saved in:
Bibliographic Details
Main Authors: Andrew Bottley, Nicola M Phillips, Thomas E Webb, Anne E Willis, Keith A Spriggs
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0013030&type=printable
Tags: Add Tag
No Tags, Be the first to tag this record!