Identification of Orch3, a locus controlling dominant resistance to autoimmune orchitis, as kinesin family member 1C.

Identification of Orch3, a locus controlling dominant resistance to autoimmune orchitis, as kinesin family member 1C.

Experimental autoimmune orchitis (EAO), the principal model of non-infectious testicular inflammatory disease, can be induced in susceptible mouse strains by immunization with autologous testicular homogenate and appropriate adjuvants. As previously established, the genome of DBA/2J mice encodes gen...

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Main Authors: Roxana del Rio, Ryan D McAllister, Nathan D Meeker, Emma H Wall, Jeffrey P Bond, Vasileios C Kyttaris, George C Tsokos, Kenneth S K Tung, Cory Teuscher
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1003140&type=printable
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https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1003140&type=printable

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