Phenotypic characterization and complete genome of a tumorigenic pathobiont Escherichia coli LI60C3

Phenotypic characterization and complete genome of a tumorigenic pathobiont Escherichia coli LI60C3

Abstract Background Symbiotic microbes benefit the host, but the emergence of pathobionts leads to disease. An invasive Escherichia coli LI60C3, isolated from mouse colonocytes, shows colitogenic and tumorigenic properties. Despite extensive research on the role of microbiota in colorectal cancer (C...

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Main Authors: Linda Chia-Hui Yu, Shu-Chen Wei, Yi-Hsuan Li, Chung-Yen Huang, Yu-Chen Pai, Yuan-Mao Hung, Liang-Chuan Lai, Yen-Hsuan Ni
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Gut Pathogens
Subjects:
Colorectal cancer microbiome
Tumorigenic E. coli
Invasive pathobionts
Comparative genomics
Complete genome sequencing
Intestinal epithelial cells
Online Access:https://doi.org/10.1186/s13099-025-00732-1
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https://doi.org/10.1186/s13099-025-00732-1

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