Integration of DNA Methylome and Transcriptome Analysis to Identify Novel Epigenetic Targets in the Acute Kidney Injury–Chronic Kidney Disease Transition

Integration of DNA Methylome and Transcriptome Analysis to Identify Novel Epigenetic Targets in the Acute Kidney Injury–Chronic Kidney Disease Transition

(1) Background: the epigenetic mechanisms underlying the progression from acute kidney injury (AKI) to chronic kidney disease (CKD) remain poorly understood; (2) Methods: to investigate this process, we conducted genome-wide DNA methylation sequencing to map the epigenetic changes during the AKI-CKD...

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Bibliographic Details
Main Authors: Xumin Zheng, Xinru Guo, Yuhao Chen, Kaiting Zhuang, Na Gong, Yifei Fu, Yanjun Liang, Yue Xu, Siyang Wang, Wenjuan Wang, Xiangmei Chen, Guangyan Cai
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Biomolecules
Subjects:
epigenetics
DNA methylation
AKI-CKD transition
Online Access:https://www.mdpi.com/2218-273X/15/4/498
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