Expression of human superoxide dismutase (SOD) 1 G93A and chlorovirus ATCV-1 SOD increases the response of macrophages to inflammatory stimulants, including ATCV-1 major capsid protein glycans

Expression of human superoxide dismutase (SOD) 1 G93A and chlorovirus ATCV-1 SOD increases the response of macrophages to inflammatory stimulants, including ATCV-1 major capsid protein glycans

One cause of familial Amyotrophic Lateral Sclerosis (ALS) is a mutation in Super Oxide Dismutase 1 (SOD1) whereby amino acid 93 is alanine instead of glycine (SOD1-G93A). Transgenic mice expressing human SOD1-G93A pathogenic variant develop motor neuron disease (MND), similar to ALS. Humans with ALS...

Full description

Saved in:
Bibliographic Details
Main Authors: Thomas M. Petro, Ahmed Esmael, Gary L. Pattee, Fiyad Al-Sarmi, Fabrizio Chiodo, Irina V. Agarkova, David D. Dunigan, James L. Van Etten
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Immunobiology
Online Access:http://www.sciencedirect.com/science/article/pii/S0171298525000154
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

http://www.sciencedirect.com/science/article/pii/S0171298525000154

Similar Items