Developing an in vitro osteochondral micro-physiological system for modeling cartilage-bone crosstalk in arthritis

IntroductionArthritis, a disease affecting over 50 million adults in the United States, encompasses many different conditions involving joints and surrounding tissues. Disease development, progression, and subsequent treatment is dependent on many different factors, including the relationship betwee...

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Main Authors: Kyra W. Y. Smith, Stephanie L. Fung, Hsin-Fang Wu, Irene Chiesa, Giovanni Vozzi, Carmelo De Maria, Riccardo Gottardi
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1495613/full
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