QSAR, docking and pharmacokinetic studies of 2,4-diphenyl indenol [1,2-B] pyridinol derivatives targeting breast cancer receptors

This study presents a computational approach for designing potent compounds against breast cancer. A robust quantitative structure-activity relationship (QSAR) model, developed using genetic algorithms and multilinear regression analysis, predicts chemical activity (pGI50) against breast cancer rece...

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Bibliographic Details
Main Authors: Auwal Isa, Adamu Uzairu, umar Umar, Muhammad Tukur Ibrahim, Abdullahi Umar
Format: Article
Language:English
Published: Iranian Chemical Science and Technologies Association 2024-04-01
Series:Journal of Chemistry Letters
Subjects:
Online Access:https://www.jchemlett.com/article_187161_9e11dbad6e377f8bc2aaadc446f85d36.pdf
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