Molecular dynamics guided identification of a brighter variant of superfolder Green Fluorescent Protein with increased photobleaching resistance

Abstract Fluorescent proteins (FPs) are a crucial tool for cell imaging, but with developments in fluorescence microscopy and researcher requirements there is still a need to develop brighter versions that remain fluorescent for longer. Using short time-scale molecular dynamics-based modelling to pr...

Full description

Saved in:
Bibliographic Details
Main Authors: Rochelle D. Ahmed, W. David Jamieson, Danoo Vitsupakorn, Athena Zitti, Kai A. Pawson, Oliver K. Castell, Peter D. Watson, D. Dafydd Jones
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:Communications Chemistry
Online Access:https://doi.org/10.1038/s42004-025-01573-4
Tags: Add Tag
No Tags, Be the first to tag this record!