DNA methylation and bronchiectasis: a Mendelian randomization analysis to investigate causal link and therapeutic target

This study aims to discover drug targeted genes and explore the potential epigenetics mechanisms in bronchiectasis. Cis-expression quantitative trait locus (eQTL) was obtained as exposure, and bronchiectasis from the FinnGen cohort was used as outcome. Mendelian Randomization (MR) was performed to i...

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Bibliographic Details
Main Authors: Jiangyue Qin, Bi Ran, Lian Liu, Ping Li, Zhenni Chen, Diandian Li, Yongchun Shen, Fuqiang Wen
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Epigenetics
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Online Access:https://www.tandfonline.com/doi/10.1080/15592294.2025.2521622
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