Unveiling chromatin dynamics with virtual epigenome

Abstract The three-dimensional organization of chromatin is essential for gene regulation and cellular function, with epigenome playing a key role. Hi-C methods have expanded our understanding of chromatin interactions, but their high cost and complexity limit their use. Existing models for predicti...

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Bibliographic Details
Main Authors: Ming-Yu Lin, Yu-Cheng Lo, Jui-Hung Hung
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-58481-3
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