Disease severity and minimal clinically important differences in clinical outcome assessments for Alzheimer's disease clinical trials

Disease severity and minimal clinically important differences in clinical outcome assessments for Alzheimer's disease clinical trials

Abstract Introduction This study estimated the minimal clinically important difference (MCID) for Mini Mental State Examination, Clinical Dementia Rating Scale sum of boxes, and Functional Activities Questionnaire across the Alzheimer's disease (AD) spectrum. Methods Retrospective analysis of t...

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Bibliographic Details
Main Authors: J. Scott Andrews, Urvi Desai, Noam Y. Kirson, Miriam L. Zichlin, Daniel E. Ball, Brandy R. Matthews
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Alzheimer’s & Dementia: Translational Research & Clinical Interventions
Subjects:
Alzheimer's disease
MCID
MMSE
CDR
FAQ
Meaningful decline
Online Access:https://doi.org/10.1016/j.trci.2019.06.005
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https://doi.org/10.1016/j.trci.2019.06.005

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