Skin melanoma cells produce diverse gelsolin (GSN) isoforms, which play non-redundant roles in cells’ proliferation and motility

Skin melanoma cells produce diverse gelsolin (GSN) isoforms, which play non-redundant roles in cells’ proliferation and motility

Abstract Background Skin melanoma is a malignant tumor that becomes increasingly difficult to treat when diagnosed late. Previously, we demonstrated that high levels of gelsolin (GSN) correlate with the advanced stages of cutaneous melanoma. GSN can be produced as various isoforms due to alternative...

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Main Authors: Ewa Mazurkiewicz-Stanek, Aleksandra Makowiecka, Iryna Kopernyk, Michał Majkowski, Anna Boguszewska-Czubara, Tomasz Trombik, Paweł Karpiński, Piotr Donizy, Antonina J. Mazur
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Cancer Cell International
Subjects:
Gelsolin (GSN)
Isoforms
Skin melanoma
Motility
Adhesion
Cancer
Online Access:https://doi.org/10.1186/s12935-025-03876-x
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https://doi.org/10.1186/s12935-025-03876-x

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