Circuit mechanism underlying fragmented sleep and memory deficits in 16p11.2 deletion mouse model of autism

Circuit mechanism underlying fragmented sleep and memory deficits in 16p11.2 deletion mouse model of autism

Summary: Sleep disturbances are prevalent in children with autism spectrum disorder (ASD). Strikingly, sleep problems are positively correlated with the severity of ASD symptoms, such as memory impairment. However, the neural mechanisms underlying sleep disturbances and cognitive deficits in ASD are...

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Main Authors: Ashley Choi, Bowon Kim, Eleanor Labriola, Alyssa Wiest, Yingqi Wang, Jennifer Smith, Hyunsoo Shin, Xi Jin, Isabella An, Jiso Hong, Hanna Antila, Steven Thomas, Janardhan P. Bhattarai, Kevin Beier, Minghong Ma, Franz Weber, Shinjae Chung
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:iScience
Subjects:
Behavioral neuroscience
Molecular neuroscience
Cellular neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224025100
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http://www.sciencedirect.com/science/article/pii/S2589004224025100

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