Improving the phenotype predictions of a yeast genome‐scale metabolic model by incorporating enzymatic constraints

Abstract Genome‐scale metabolic models (GEMs) are widely used to calculate metabolic phenotypes. They rely on defining a set of constraints, the most common of which is that the production of metabolites and/or growth are limited by the carbon source uptake rate. However, enzyme abundances and kinet...

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Bibliographic Details
Main Authors: Benjamín J Sánchez, Cheng Zhang, Avlant Nilsson, Petri‐Jaan Lahtvee, Eduard J Kerkhoven, Jens Nielsen
Format: Article
Language:English
Published: Springer Nature 2017-08-01
Series:Molecular Systems Biology
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Online Access:https://doi.org/10.15252/msb.20167411
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