Enzyme-catalyzed synthesis of mannose ester and its enhancement of tanshinone and glycyrrhetinic acid lipid nanoparticles

Objective: To improve the efficiency of drug delivery, a mannose vinyl stearate mannose ligand (Man ligand) with active liver-targeting properties was synthesized. Methods: Non-aqueous enzymatic synthesis was used to modify the structure of mannose. Glycyrrhetinic acid-tanshinone lipid nanoparticles...

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Bibliographic Details
Main Authors: Yue Li, Jiexuan Wang, Xiuli Wang, Xue Guo
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Journal of Traditional Chinese Medical Sciences
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Online Access:http://www.sciencedirect.com/science/article/pii/S2095754825000420
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