Sarcolemma resilience and skeletal muscle health require O-mannosylation of dystroglycan

Sarcolemma resilience and skeletal muscle health require O-mannosylation of dystroglycan

Abstract Background Maintaining the connection between skeletal muscle fibers and the surrounding basement membrane is essential for muscle function. Dystroglycan (DG) serves as a basement membrane extracellular matrix (ECM) receptor in many cells, and is also expressed in the outward-facing membran...

Full description

Saved in:
Bibliographic Details
Main Authors: Jeffrey M. Hord, Sarah Burns, Tobias Willer, Matthew M. Goddeeris, David Venzke, Kevin P. Campbell
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Skeletal Muscle
Subjects:
Dystroglycan
O-mannosylation
Protein O-mannosyltransferase 1 (POMT1)
Like-acetylglucosaminyltransferase 1 (LARGE1)
Matriglycan
Skeletal muscle
Online Access:https://doi.org/10.1186/s13395-024-00370-2
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1186/s13395-024-00370-2

Similar Items