Tetrahydrofurfuryl Nitrate: A New Organic Nitrate Induces Hypotension and Vasorelaxation Without Vascular Tolerance Induction

Tetrahydrofurfuryl Nitrate: A New Organic Nitrate Induces Hypotension and Vasorelaxation Without Vascular Tolerance Induction

The development of new organic nitrates is still relevant due to the clinical limitations of their use. Tetrahydrofurfuryl nitrate (NTHF) is a new organic nitrate obtained through a synthetic route of sugarcane. The aim of this research was to investigate the cardiovascular effects promoted by NTHF...

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Main Authors: Maria do Carmo de Alustau-Fernandes, Fabíola Fialho Furtado Gouvêa, Natália Tabosa Machado Calzerra, Tays Amanda Felisberto Gonçalves, Valéria Lopes de Assis, Walma Pereira de Vasconcelos, Petrônio Filgueiras de Athayde-Filho, Robson Cavalcante Veras, Thyago Moreira de Queiroz, Isac Almeida de Medeiros
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Journal of Vascular Diseases
Subjects:
blood pressure
hypotension
nitric oxide donor
organic nitrate
potassium channels
vasodilation
Online Access:https://www.mdpi.com/2813-2475/3/4/34
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