Physicochemical investigation of phenobarbital sodium interactions with anionic bile salt micelles: Binding, partitioning, and micellization behavior

Understanding drug-surfactant interactions is crucial for optimizing pharmaceutical formulations. This study aimed to comprehensively investigate the physicochemical interactions between phenobarbital sodium (PS) and two anionic bile salts, sodium cholate (NaC) and sodium deoxycholate (NaDC), in aqu...

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Bibliographic Details
Main Authors: Haytham Abuissa, Ashraf EL-Hashani
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Next Materials
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2949822825003922
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