Prognostic Significance of Macrophage Phenotypes in Peri-Tumoral Normal Tissue of Early-Stage Breast Cancer

Prognostic Significance of Macrophage Phenotypes in Peri-Tumoral Normal Tissue of Early-Stage Breast Cancer

In recent years, tumor-infiltrating inflammatory cells within the tumor microenvironment have been extensively studied. However, much less is known about inflammatory cells in the normal tissue surrounding tumors. In this study, we assess the prognostic significance of tumor-associated macrophages (...

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Main Authors: Marcel Hirschmann, Sören Schnellhardt, Matthias Rübner, Sarah Segelhorst, Oliver Ott, Ramona Erber, Christoph Daniel, Maike Büttner-Herold, Paul Gass, Rainer Fietkau, Luitpold Distel
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Cells
Subjects:
early-stage breast cancer
normal tissue
M1
M2
macrophages
tumor-infiltrating inflammatory cells
Online Access:https://www.mdpi.com/2073-4409/14/11/828
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https://www.mdpi.com/2073-4409/14/11/828

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