Single-cell eQTL mapping of human endogenous retroviruses reveals cell type-specific genetic regulation in autoimmune diseases

Abstract Human endogenous retroviruses constitute a significant portion of the human genome and play complex roles in gene regulation and disease processes. However, the expression pattern and disease associations of specific retroviral loci remain pooly understood. This study examines the expressio...

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Bibliographic Details
Main Authors: Fan Zhu, Yi Liu, Jiehao Lei, Xinxing Li, Zexu Jiang, Xuan Dong, Ying Gu, Young Li
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-62779-7
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