Prognostic impact of co-mutations in adults with IDH1/2-mutated acute myeloid leukemia

Prognostic impact of co-mutations in adults with IDH1/2-mutated acute myeloid leukemia

Acute myeloid leukemia (AML) is characterized by the accumulation of cytogenetic and molecular abnormalities. Isocitrate dehydrogenase 1 and 2 (IDH1/2) mutations occur in 11% to 20% of adults with AML. The outcome of IDH1/2-mutated AML is heterogeneous and affected by co-mutational patterns. We retr...

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Main Authors: Anli Lai, Wenbing Liu, Chunlin Zhou, Yan Li, Shuning Wei, Kaiqi Liu, Benfa Gong, Xiaoyuan Gong, Yuntao Liu, Guangji Zhang, Junping Zhang, Runxia Gu, Shaowei Qiu, Bingcheng Liu, Ying Wang, Hui Wei, Yingchang Mi, Jianxiang Wang
Format: Article
Language:English
Published: Wolters Kluwer Health 2025-06-01
Series:Blood Science
Online Access:http://journals.lww.com/10.1097/BS9.0000000000000231
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http://journals.lww.com/10.1097/BS9.0000000000000231

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