Berbamine suppresses intestinal SARS-CoV-2 infection via a BNIP3-dependent autophagy blockade

Berbamine suppresses intestinal SARS-CoV-2 infection via a BNIP3-dependent autophagy blockade

SARS-CoV-2, the causative virus of COVID-19, continues to threaten global public health. COVID-19 is a multi-organ disease, causing not only respiratory distress, but also extrapulmonary manifestations, including gastrointestinal symptoms with SARS-CoV-2 RNA shedding in stool long after respiratory...

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Bibliographic Details
Main Authors: Alexandra P. M. Cloherty, Anusca G. Rader, Kharishma S. Patel, Jimena Pérez-Vargas, Connor A. H. Thompson, Siobhan Ennis, Masahiro Niikura, Manon E. Wildenberg, Vanesa Muncan, Renée R. C. E. Schreurs, François Jean, Carla M. S. Ribeiro
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Emerging Microbes and Infections
Subjects:
Viral entry routes
drug repurposing
extrapulmonary COVID-19
host-directed antiviral therapy
autophagy
Human intestinal organoids
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2023.2195020
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https://www.tandfonline.com/doi/10.1080/22221751.2023.2195020

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