Posttranslational modifications of YAP/TAZ: molecular mechanisms and therapeutic opportunities

Abstract Yes-associated protein (YAP) and its paralog, transcriptional coactivator with PDZ-binding motif (TAZ), are critical effectors of the Hippo pathway, as well as other biochemical and biophysical signals. Through their interaction with DNA-binding partners, YAP/TAZ can modulate the transcript...

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Bibliographic Details
Main Authors: Zhenxiong Zhang, Peiheng He, Li Yang, Jun Gong, Renyi Qin, Min Wang
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Cellular & Molecular Biology Letters
Subjects:
Online Access:https://doi.org/10.1186/s11658-025-00760-4
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