Topological data analysis captures horizontal gene transfer in antimicrobial resistance gene families among clinically relevant bacteria

Topological data analysis captures horizontal gene transfer in antimicrobial resistance gene families among clinically relevant bacteria

Antibiotic resistance, projected to cause 10 million deaths annually by 2050, remains a critical health threat. Hospitals drive multidrug resistance via horizontal gene transfer. The 2023 Critical Assessment of Massive Data Analysis challenge presents resistance markers from 146 Johns Hopkins bacter...

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Bibliographic Details
Main Authors: Shaday Guerrero-Flores, Haydeé Contreras-Peruyero, José María Ibarra-Rodríguez, José Abel Lovaco-Flores, Francisco Santiago Nieto-de la Rosa, Fernando Fontove-Herrera, Nelly Sélem-Mojica
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Microbiology
Subjects:
antimicrobial resistance (AMR)
persistence barcode
horizontal gene transfer (HGT)
topological data analysis
persistent homology
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1461293/full
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https://www.frontiersin.org/articles/10.3389/fmicb.2025.1461293/full

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