Cytotoxic effects of Methoxy-substituted Chalcones on glioblastoma stem cells: Computational target prediction and therapeutic insights

Cytotoxic effects of Methoxy-substituted Chalcones on glioblastoma stem cells: Computational target prediction and therapeutic insights

The prognosis for patients diagnosed with glioblastoma remains dismal with an average survival of about 15 months. Recently, it has been shown that glioblastoma stem-like cells (GSCs) drive tumor progression and are responsible for tumor regrowth following treatment; therefore, successful eliminatio...

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Bibliographic Details
Main Authors: Eduardo A. Veliz, Athina Yoham, Anastasiya Drandarov, Esther L. Abadi, Emanuella M. Brito, Maria Moreno Hollweg, Venkatesh Shanbhag, Roger M. Leblanc, Steven Vanni, Regina M. Graham
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Results in Chemistry
Subjects:
Glioblastoma
Glioblastoma stem cell
Chalcones
Trimethoxy
Online Access:http://www.sciencedirect.com/science/article/pii/S2211715625001055
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