Glucose transporter 1 in vascular smooth muscle cells is dispensable for abdominal aortic aneurysm induced by angiotensin II

Glucose transporter 1 in vascular smooth muscle cells is dispensable for abdominal aortic aneurysm induced by angiotensin II

Treatment with an inhibitor of glucose use via glucose transporters (GLUT) has been shown to attenuate experimental abdominal aortic aneurysm (AAA) development in mice. Vascular smooth muscle cell (VSMC) signaling seems to be essential for angiotensin II (Ang II)-induced AAA in mice. Accordingly, we...

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Main Authors: Keiichi Torimoto, MD, PhD, Hymavathi Reddy Vari, PhD, Yuki Nakayama, MD, PhD, Hirotoshi Utsunomiya, PhD, Masatoshi Takeda, MD, PhD, Tomoki Hashimoto, MD, PhD, Victor Rizzo, PhD, Satoru Eguchi, MD, PhD
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:JVS - Vascular Science
Subjects:
Glucose transporter
Abdominal aortic aneurysm
Hypertension
Angiotensin II
Online Access:http://www.sciencedirect.com/science/article/pii/S2666350324000816
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