Urinary Metabolic Profiling During Epileptogenesis in Rat Model of Lithium–Pilocarpine-Induced Temporal Lobe Epilepsy

Urinary Metabolic Profiling During Epileptogenesis in Rat Model of Lithium–Pilocarpine-Induced Temporal Lobe Epilepsy

<b>Background/Objectives</b>: Temporal lobe epilepsy (TLE) often develops following an initial brain injury, where specific triggers lead to epileptogenesis—a process transforming a healthy brain into one prone to spontaneous, recurrent seizures. Although electroencephalography (EEG) rem...

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Main Authors: Fatma Merve Antmen, Emir Matpan, Ekin Dongel Dayanc, Eylem Ozge Savas, Yunus Eken, Dilan Acar, Alara Ak, Begum Ozefe, Damla Sakar, Ufuk Canozer, Sehla Nurefsan Sancak, Ozkan Ozdemir, Osman Ugur Sezerman, Ahmet Tarık Baykal, Mustafa Serteser, Guldal Suyen
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Biomedicines
Subjects:
epilepsy
urine
nuclear magnetic resonance
metabolomics
epileptogenesis
rat
Online Access:https://www.mdpi.com/2227-9059/13/3/588
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