TCF3 as a multidimensional biomarker: oncogenicity, genomic alterations, and immune landscape in pan-cancer analysis

TCF3 as a multidimensional biomarker: oncogenicity, genomic alterations, and immune landscape in pan-cancer analysis

Transcription factor 3 (TCF3), a pivotal member of the TCF/LEF family, plays a critical role in tumorigenesis. Nonetheless, its impact on the tumor microenvironment (TME) and cancer phenotypes remains elusive. We perform an exhaustive analysis of TCF3 expression, DNA variation profiles, prognostic i...

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Bibliographic Details
Main Authors: Nie Huiling, Yu Yang, Zhou Siqi, Xu Yue, Chen Xi, Qin Xun, Liu Zhangyu, Huang Jiayu, Zhang Hailiang, Yao Jin, Jiang Qin, Wei Bingbing, Qin Xiaojian
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2024-08-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
TCF/LEF family
TCF3
pan-cancer analysis
prognosis
tumor microenvironment (TME)
epithelial-mesenchymal transition (EMT)
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2024126
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https://www.sciengine.com/doi/10.3724/abbs.2024126

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