Control of bone mass and remodeling by PTH receptor signaling in osteocytes.

Control of bone mass and remodeling by PTH receptor signaling in osteocytes.

Osteocytes, former osteoblasts buried within bone, are thought to orchestrate skeletal adaptation to mechanical stimuli. However, it remains unknown whether hormones control skeletal homeostasis through actions on osteocytes. Parathyroid hormone (PTH) stimulates bone remodeling and may cause bone lo...

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Main Authors: Charles A O'Brien, Lilian I Plotkin, Carlo Galli, Joseph J Goellner, Arancha R Gortazar, Matthew R Allen, Alexander G Robling, Mary Bouxsein, Ernestina Schipani, Charles H Turner, Robert L Jilka, Robert S Weinstein, Stavros C Manolagas, Teresita Bellido
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-08-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0002942&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0002942&type=printable

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