Fabrication of Thymoquinone and Ascorbic Acid-Loaded Spanlastics Gel for Hyperpigmentation: In Vitro Release, Cytotoxicity, and Skin Permeation Studies

Fabrication of Thymoquinone and Ascorbic Acid-Loaded Spanlastics Gel for Hyperpigmentation: In Vitro Release, Cytotoxicity, and Skin Permeation Studies

<b>Background/Objectives</b>: The demand for a safe compound for hyperpigmentation is continuously increasing. Bioactive compounds such as thymoquinone (TQ) and ascorbic acid (AA) induce inhibition of melanogenesis with a high safety profile. The aim of this study was to design and evalu...

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Bibliographic Details
Main Authors: Ahlam Zaid Alkilani, Rua’a Alkhaldi, Haneen A. Basheer, Bassam I. Amro, Maram A. Alhusban
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Pharmaceutics
Subjects:
dermal
spanlastics
thymoquinone
ascorbic acid
hyperpigmentation
nanomedicine
Online Access:https://www.mdpi.com/1999-4923/17/1/48
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