Progranulin Plays a Protective Role in Pneumococcal Meningitis by Inhibiting Pyroptosis

ABSTRACT Objective Pneumococcal meningitis is a serious infectious disease with a high mortality rate and a global presence, and survivors have different degrees of neurological sequelae as a consequence of the host response to the infection. Progranulin (PGRN) is a multifunctional autocrine growth...

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Bibliographic Details
Main Authors: Jingyao Wang, Lihua Kang, Wenlong Xu, Jiangming Xiao, Yajun Min, Sijie Li, Changlong Zhou, Yibing Yin, Xuemei Zhang, Qun Zhang
Format: Article
Language:English
Published: Wiley 2025-02-01
Series:Immunity, Inflammation and Disease
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Online Access:https://doi.org/10.1002/iid3.70140
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