Monitoring the long-term molecular epidemiology of the pneumococcus and detection of potential 'vaccine escape' strains.

Monitoring the long-term molecular epidemiology of the pneumococcus and detection of potential 'vaccine escape' strains.

<h4>Background</h4>While the pneumococcal protein conjugate vaccines reduce the incidence in invasive pneumococcal disease (IPD), serotype replacement remains a major concern. Thus, serotype-independent protection with vaccines targeting virulence genes, such as PspA, have been pursued....

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Main Authors: Gagan A Pandya, M Catherine McEllistrem, Pratap Venepally, Michael H Holmes, Behnam Jarrahi, Ravi Sanka, Jia Liu, Svetlana A Karamycheva, Yun Bai, Robert D Fleischmann, Scott N Peterson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0015950&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0015950&type=printable

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