Computational and experimental discovery of peptide inhibitors targeting survivin for therapeutic potential in cancer

Abstract Evidence indicates that the survivin protein is overexpressed in various types of cancer. Survivin belongs to the inhibitors of apoptosis proteins (IAPs) family, which plays a crucial role in preventing apoptosis and regulating the cell cycle. This protein has a multifaceted function in the...

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Bibliographic Details
Main Authors: Seyedeh Fatemeh Ahmadi, Seyed Shahriar Arab, Hamidreza Samadikhah
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-13110-3
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