The Novel Elemene Derivative, OMe-Ph-Elemene, Attenuates Oxidative Phosphorylation and Facilitates Apoptosis by Inducing Intracellular Reactive Oxygen Species

The Novel Elemene Derivative, OMe-Ph-Elemene, Attenuates Oxidative Phosphorylation and Facilitates Apoptosis by Inducing Intracellular Reactive Oxygen Species

The incidence and mortality rates of colorectal cancer have been steadily increasing, making it one of the most prevalent cancers globally. Although current chemotherapy drugs have shown some efficacy in treating this disease, their associated side effects necessitate the development of more effecti...

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Bibliographic Details
Main Authors: Jianhua Guo, Jiayi Wang, Shuhao Fan, Mucong Gao, Guodu Liu, Yong Xia
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Antioxidants
Subjects:
Elemene
colorectal cancer
oxidative stress
oxidative phosphorylation
apoptosis
Online Access:https://www.mdpi.com/2076-3921/13/12/1499
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