Protection against lethal HAdV-4 challenge in STAT1 mice by novel human monoclonal antibodies

Protection against lethal HAdV-4 challenge in STAT1 mice by novel human monoclonal antibodies

IntroductionHuman adenovirus serotype 4 (HAdV-4) is an epidemic pathogen associated with severe acute respiratory disease (ARD) in both pediatric and adult populations. Currently, no available vaccine or therapeutic interventions specifically targeting adenoviruses are available.MethodsIn this study...

Full description

Saved in:
Bibliographic Details
Main Authors: Xinyi Zhang, Zhongge Zhu, Peijie Zhai, Peng Lv, You Yang, Chuanhang Cheng, Busen Wang, Ting Fang, Guanying Zhang, Xiangyang Chi, Jianmin Li, Wei Chen, Yunzhu Dong
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Immunology
Subjects:
human adenovirus serotype 4
neutralizing monoclonal antibody
stat1-/- transgenic mice
structural biology
TRIM21
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1613945/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2025.1613945/full

Similar Items