A novel pThr217 tau monoclonal antibody reveals neuropathological heterogeneity in tauopathies
Abstract Tauopathies are a group of clinically and neuropathologically diverse neurodegenerative disorders defined by the abnormal aggregation of tau protein. While tau is normally soluble with limited secondary structure, pathological tau is characterized by hyperphosphorylation and assembly into f...
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| Main Authors: | Giavanna Paterno, Brach M. Bell, Kimberly-Marie M. Gorion, Stephan Quintin, Stefan Prokop, Benoit I. Giasson |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-06-01
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| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-04291-y |
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