The oxidative-stress-senescence axis in keratoconus: new insights into corneal degeneration

The oxidative-stress-senescence axis in keratoconus: new insights into corneal degeneration

Keratoconus is a bilateral and asymmetric degenerative eye disease that causes corneal thinning and bowing, leading to irregular astigmatism and vision loss. Although environmental and genetic factors contribute to the disease’s development, the exact cause and underlying pathological mechanism rema...

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Bibliographic Details
Main Authors: Maria Laura Passaro, Michele Rinaldi, Valentina Morgera, Antonia Feola, Vito Romano, Mario Troisi, Diego Strianese, Raffaele Piscopo, Samantha Messina, Antonella Romano, Antonio Porcellini, Antonio Pezone, Ciro Costagliola
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Molecular Biosciences
Subjects:
keratoconus
oxidative stress
mitochondrial dysfunction
senescence
inflammation
antioxidant therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2025.1539542/full
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https://www.frontiersin.org/articles/10.3389/fmolb.2025.1539542/full

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